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Substitution of Human Papillomavirus Type 16 L2 Neutralizing Epitopes Into L1 Surface Loops: The Effect on Virus-Like Particle Assembly and Immunogenicity

Cervical cancer caused by infection with human papillomaviruses (HPVs) is the fourth most common cancer in women globally, with the burden mainly in developing countries due to limited healthcare resources. Current vaccines based on virus-like particles (VLPs) assembled from recombinant expression o...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Chabeda, Aleyo, van Zyl, Albertha R., Rybicki, Edward P., Hitzeroth, Inga I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597877/
https://ncbi.nlm.nih.gov/pubmed/31281327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2019.00779
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