Porcine deltacoronavirus enters cells via two pathways: A protease-mediated one at the cell surface and another facilitated by cathepsins in the endosome

Porcine deltacoronavirus (PDCoV) is a pathogen belonging to the genus Deltacoronavirus that in 2014 caused outbreaks of piglet diarrhea in the United States. To identify suitable therapeutic targets, a more comprehensive understanding of the viral entry pathway is required, particularly of the role...

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Udgivet i:J Biol Chem
Main Authors: Zhang, Jialin, Chen, Jianfei, Shi, Da, Shi, Hongyan, Zhang, Xin, Liu, Jianbo, Cao, Liyan, Zhu, Xiangdong, Liu, Ye, Wang, Xiaobo, Ji, Zhaoyang, Feng, Li
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597833/
https://ncbi.nlm.nih.gov/pubmed/31068417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007779
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