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Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DMT) in Mammalian Brain

N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dean, Jon G., Liu, Tiecheng, Huff, Sean, Sheler, Ben, Barker, Steven A., Strassman, Rick J., Wang, Michael M., Borjigin, Jimo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597727/
https://ncbi.nlm.nih.gov/pubmed/31249368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45812-w
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