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Interplay of Darwinian Selection, Lamarckian Induction and Microvesicle Transfer on Drug Resistance in Cancer

Development of drug resistance in cancer has major implications for patients’ outcome. It is related to processes involved in the decrease of drug efficacy, which are strongly influenced by intratumor heterogeneity and changes in the microenvironment. Heterogeneity arises, to a large extent, from ge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Álvarez-Arenas, Arturo, Podolski-Renic, Ana, Belmonte-Beitia, Juan, Pesic, Milica, Calvo, Gabriel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597577/
https://ncbi.nlm.nih.gov/pubmed/31249353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45863-z
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