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Facilitation and inhibition of firing activity and N-methyl-D-aspartate-evoked responses of CA1 hippocampal pyramidal cells by alpha7 nicotinic acetylcholine receptor selective compounds in vivo

Alpha7 nicotinic acetylcholine receptors (nAChRs) are promising novel targets for the treatment of neurocognitive disorders. Although the cognitive enhancer potential of alpha7 nAChR agonists and positive allosteric modulators (PAMs) has been confirmed in several preclinical animal models, there are...

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Publicat a:Sci Rep
Autors principals: Bali, Zsolt Kristóf, Nagy, Lili Veronika, Budai, Dénes, Hernádi, István
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597544/
https://ncbi.nlm.nih.gov/pubmed/31249369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45796-7
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