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IL-10 producing B cells rescue mouse fetuses from inflammation-driven fetal death and are able to modulate T cell immune responses

Understanding the mechanisms leading to fetal death following maternal subclinical infections is crucial to develop new therapeutic strategies. Here we addressed the relevance of IL-10 secreting B cells (B10) in the maintenance of the immune balance during gestation. µMT females lacking mature B cel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Busse, Mandy, Campe, Kim-Norina Jutta, Nowak, Desiree, Schumacher, Anne, Plenagl, Susanne, Langwisch, Stefanie, Tiegs, Gisa, Reinhold, Annegret, Zenclussen, Ana Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597542/
https://ncbi.nlm.nih.gov/pubmed/31249364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45860-2
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