Below the surface: The inner lives of TLR4 and TLR9

TLRs are a class of pattern recognition receptors (PRRs) that detect invading microbes by recognizing pathogen‐associated molecular patterns (PAMPs). Upon PAMP engagement, TLRs activate a signaling cascade that leads to the production of inflammatory mediators. The localization of TLRs, either on th...

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Bibliografske podrobnosti
izdano v:J Leukoc Biol
Main Authors: Marongiu, Laura, Gornati, Laura, Artuso, Irene, Zanoni, Ivan, Granucci, Francesca
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Intracellular Danger Sensors Fueling Inflammation and Autoimmunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597292/
https://ncbi.nlm.nih.gov/pubmed/30900780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MIR1218-483RR
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