Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells

Mobilized peripheral blood has become the primary source of hematopoietic stem and progenitor cells (HSPCs) for stem cell transplantation, with a 5-day course of granulocyte colony-stimulating factor (G-CSF) as the most common regimen used for HSPC mobilization. The CXCR4 inhibitor plerixafor is a m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Karpova, Darja, Rettig, Michael P., Ritchey, Julie, Cancilla, Daniel, Christ, Stephanie, Gehrs, Leah, Chendamarai, Ezhilarasi, Evbuomwan, Moses O., Holt, Matthew, Zhang, Jingzhu, Abou-Ezzi, Grazia, Celik, Hamza, Wiercinska, Eliza, Yang, Wei, Gao, Feng, Eissenberg, Linda G., Heier, Richard F., Arnett, Stacy D., Meyers, Marvin J., Prinsen, Michael J., Griggs, David W., Trumpp, Andreas, Ruminski, Peter G., Morrow, Dwight M., Bonig, Halvard B., Link, Daniel C., DiPersio, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597242/
https://ncbi.nlm.nih.gov/pubmed/31085833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124738
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