T cell receptor grafting allows virological control of hepatitis B virus infection

T cell therapy is a promising means to treat chronic hepatitis B virus (HBV) infection and HBV-associated hepatocellular carcinoma. T cells engineered to express an HBV-specific T cell receptor (TCR) may cure an HBV infection upon adoptive transfer. We investigated the therapeutic potential and safe...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Wisskirchen, Karin, Kah, Janine, Malo, Antje, Asen, Theresa, Volz, Tassilo, Allweiss, Lena, Wettengel, Jochen M., Lütgehetmann, Marc, Urban, Stephan, Bauer, Tanja, Dandri, Maura, Protzer, Ulrike
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597229/
https://ncbi.nlm.nih.gov/pubmed/31039136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120228
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