Tumor M2-PK: A novel urine marker of bladder cancer

PURPOSE: Bladder cancer is a “Warburg-like” tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in particular PKM2 dimer, as a urinary biomarker of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Weiya, Woolbright, Benjamin L., Pirani, Karim, Didde, Ryan, Abbott, Erika, Kaushik, Gaurav, Martin, Paige, Hamilton-Reeves, Jill, Taylor, John A., Holzbeierlein, Jeffrey M., Anant, Shrikant, Lee, Eugene K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597081/
https://ncbi.nlm.nih.gov/pubmed/31246990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218737
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