Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice

Temporal lobe epilepsy (TLE) is the most frequent form of focal epilepsies and is generally associated with malfunctioning of the hippocampal formation. Recently, a preferential loss of parvalbumin (PV) neurons has been observed in the subiculum of TLE patients and in animal models of TLE. To demons...

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Pubblicato in:J Neurosci
Autori principali: Drexel, Meinrad, Romanov, Roman A., Wood, James, Weger, Stefan, Heilbronn, Regine, Wulff, Peer, Tasan, Ramon O., Harkany, Tibor, Sperk, Günther
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596787/
https://ncbi.nlm.nih.gov/pubmed/28733354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3456-16.2017
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