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Spinal Interleukin-1β Inhibits Astrocyte Cytochrome P450c17 Expression Which Controls the Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain

We have recently demonstrated that sciatic nerve injury increases the expression of spinal cytochrome P450c17, a key neurosteroidogenic enzyme, which plays a critical role in the development of peripheral neuropathic pain. However, the modulatory mechanisms responsible for the expression of spinal P...

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Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: Choi, Sheu-Ran, Han, Ho-Jae, Beitz, Alvin J., Lee, Jang-Hern
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596369/
https://ncbi.nlm.nih.gov/pubmed/31281242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00153
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