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A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression
The serotonin-1A (5-HT1A) receptor is a key regulator of serotonergic activity and is implicated in mood and emotion. However, its post-transcriptional regulation has never been studied in humans. In the present study, we show that the “intronless” human 5-HT1A gene (HTR1A) is alternatively spliced...
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| 發表在: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596165/ https://ncbi.nlm.nih.gov/pubmed/30093565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0902-18.2018 |
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