Scaffold hybridization strategy towards potent hydroxamate-based inhibitors of Flaviviridae viruses and Trypanosoma species

Infections with Flaviviridae viruses, such as hepatitis C virus (HCV) and dengue virus (DENV) pose global health threats. Infected individuals are at risk of developing chronic liver failure or haemorrhagic fever respectively, often with a fatal outcome if left untreated. Diseases caused by tropical...

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Veröffentlicht in:Medchemcomm
Hauptverfasser: Giannakopoulou, Erofili, Pardali, Vasiliki, Frakolaki, Efseveia, Siozos, Vasileios, Myrianthopoulos, Vassilios, Mikros, Emmanuel, Taylor, Martin C., Kelly, John M., Vassilaki, Niki, Zoidis, Grigoris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2019
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596085/
https://ncbi.nlm.nih.gov/pubmed/31303998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00200f
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