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Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

BACKGROUND: Costunolide, a sesquiterpene lactone extracted from Radix Aucklandiae, has the activity against multiple cancers. However, the effect of costunolide on gastric cancer (GC) have remained to be ambiguous. In this study, we investigated the underlying mechanisms of apoptosis induced by cost...

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Détails bibliographiques
Publié dans:BMC Complement Altern Med
Auteurs principaux: Yan, Zhanpeng, Xu, Tingting, An, Zhentao, Hu, Ying, Chen, Wanzhen, Ma, Jinxia, Shao, Changle, Zhu, Fangshi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595696/
https://ncbi.nlm.nih.gov/pubmed/31242894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2569-6
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