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Coadministration of the prostaglandin F2α receptor antagonist preterm labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone
AIMS: To investigate presence or absence of clinically relevant drug interactions (pharmacokinetic and safety/tolerability) of OBE022 with standard‐of‐care medicines for preterm labour, enabling coadministration and further clinical development. METHODS: Part A: open‐label, randomized, 3‐period cros...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6595366/ https://ncbi.nlm.nih.gov/pubmed/30891820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13925 |
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