Endless Forms: Within-Host Variation in the Structure of the West Nile Virus RNA Genome during Serial Passage in Bird Hosts

RNA viruses are infamous for their high rates of mutation, which produce swarms of genetic variants within individual hosts. To date, analyses of intrahost genetic diversity have focused on the primary genome sequence. However, virus phenotypes are shaped not only by primary sequence but also by the...

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Pubblicato in:mSphere
Autori principali: Scroggs, Stacey L. P., Grubaugh, Nathan D., Sena, Johnny A., Sundararajan, Anitha, Schilkey, Faye D., Smith, Darci R., Ebel, Gregory D., Hanley, Kathryn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595145/
https://ncbi.nlm.nih.gov/pubmed/31243074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00291-19
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