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Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases

Collective cell migration occurs in many patho-physiological states, including wound healing and invasive cancer growth. The integrity of the expanding epithelial sheets depends on extracellular cues, including cell-cell and cell-matrix interactions. We show that the nano-scale topography of the ext...

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Vydáno v:Nat Commun
Hlavní autoři: Park, JinSeok, Kim, Deok-Ho, Shah, Sagar R., Kim, Hong-Nam, Kshitiz, Kim, Peter, Quiñones-Hinojosa, Alfredo, Levchenko, Andre
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594963/
https://ncbi.nlm.nih.gov/pubmed/31243273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10729-5
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