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Nutrient availability shapes methionine metabolism in p16/MTAP-deleted cells
Codeletions of gene loci containing tumor suppressors and neighboring metabolic enzymes present an attractive synthetic dependency in cancers. However, the impact that these genetic events have on metabolic processes, which are also dependent on nutrient availability and other environmental factors,...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594760/ https://ncbi.nlm.nih.gov/pubmed/31249865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav7769 |
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