Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

AIMS: Statin-related myopathy (SRM), which includes rhabdomyolysis, is an uncommon but important adverse drug reaction because the number of people prescribed statins world-wide is large. Previous association studies of common genetic variants have had limited success in identifying a genetic basis...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Floyd, James S., Bloch, Katarzyna M., Brody, Jennifer A., Maroteau, Cyrielle, Siddiqui, Moneeza K., Gregory, Richard, Carr, Daniel F., Molokhia, Mariam, Liu, Xiaoming, Bis, Joshua C., Ahmed, Ammar, Liu, Xuan, Hallberg, Pär, Yue, Qun-Ying, Magnusson, Patrik K. E., Brisson, Diane, Wiggins, Kerri L., Morrison, Alanna C., Khoury, Etienne, McKeigue, Paul, Stricker, Bruno H., Lapeyre-Mestre, Maryse, Heckbert, Susan R., Gallagher, Arlene M., Chinoy, Hector, Gibbs, Richard A., Bondon-Guitton, Emmanuelle, Tracy, Russell, Boerwinkle, Eric, Gaudet, Daniel, Conforti, Anita, van Staa, Tjeerd, Sitlani, Colleen M., Rice, Kenneth M., Maitland-van der Zee, Anke-Hilse, Wadelius, Mia, Morris, Andrew P., Pirmohamed, Munir, Palmer, Colin A. N., Psaty, Bruce M., Alfirevic, Ana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594672/
https://ncbi.nlm.nih.gov/pubmed/31242253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218115
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