ATP6V(0)d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis

V-ATPases are part of the membrane components of pathogen-containing vacuoles, although their function in intracellular infection remains elusive. In addition to organelle acidification, V-ATPases are alternatively implicated in membrane fusion and anti-inflammatory functions controlled by ATP6V(0)d...

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Publicat a:PLoS Pathog
Autors principals: Pessoa, Carina Carraro, Reis, Luiza Campos, Ramos-Sanchez, Eduardo Milton, Orikaza, Cristina Mary, Cortez, Cristian, de Castro Levatti, Erica Valadares, Badaró, Ana Carolina Benites, Yamamoto, Joyce Umbelino da Silva, D’Almeida, Vânia, Goto, Hiro, Mortara, Renato Arruda, Real, Fernando
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594656/
https://ncbi.nlm.nih.gov/pubmed/31199856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007834
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