Expression of serine/threonine protein kinase SGK1F promotes an hepatoblast state in stem cells directed to differentiate into hepatocytes

The rat pancreatic AR42J-B13 (B-13) cell line differentiates into non-replicative hepatocyte-like (B-13/H) cells in response to glucocorticoid. Since this response is dependent on an induction of serine/threonine protein kinase 1 (SGK1), this may suggest that a general pivotal role for SGK1 in hepat...

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Publicat a:PLoS One
Autors principals: Alsaeedi, Fouzeyyah, Wilson, Rachel, Candlish, Charlotte, Ibrahim, Ibrahim, Leitch, Alistair C., Abdelghany, Tarek M., Wilson, Colin, Armstrong, Lyle, Wright, Matthew C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594595/
https://ncbi.nlm.nih.gov/pubmed/31242206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218135
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