A microparticle platform for STING-targeted immunotherapy enhances natural killer cell and CD8(+) T cell-mediated anti-tumor immunity.

Immunotherapies have significantly improved cancer patient survival, but response rates are still limited. Thus, novel formulations are needed to expand the breadth of immunotherapies. Pathogen associated molecular patterns (PAMPs) can be used to stimulate an immune response, but several pathogen re...

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Pubblicato in:Biomaterials
Autori principali: Watkins-Schulz, Rebekah, Tiet, Pamela, Gallovic, Matthew D., Junkins, Robert D., Batty, Cole, Bachelder, Eric M., Ainslie, Kristy M., Ting, Jenny P.-Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594365/
https://ncbi.nlm.nih.gov/pubmed/30909112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.03.011
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