In vivo and in vitro Approaches Reveal Novel Insight Into the Ability of Epicardium-Derived Cells to Create Their Own Extracellular Environment

Human epicardium-derived cells (hEPDCs) transplanted in the NOD-SCID mouse heart after myocardial infarction (MI) are known to improve cardiac function, most likely orchestrated by paracrine mechanisms that limit adverse remodeling. It is not yet known, however, if hEPDCs contribute to preservation...

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Detalhes bibliográficos
Publicado no:Front Cardiovasc Med
Main Authors: Bax, Noortje A. M., Duim, Sjoerd N., Kruithof, Boudewijn P. T., Smits, Anke M., Bouten, Carlijn V. C., Goumans, Marie José
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cardiovascular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594358/
https://ncbi.nlm.nih.gov/pubmed/31275946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00081
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