Validation of NRG Oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer (OPC); implications for risk-based therapeutic intensity trials

BACKGROUND: RTOG-0129 recursive partitioning analysis was the basis for risk-based therapeutic intensification trials for oropharynx cancer (OPC). Whether RTOG-0129 overall survival (OS) estimates for low-, intermediate- and high-risk groups are similar in other datasets or applicable to progression...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Fakhry, Carole, Zhang, Qiang, Gillison, Maura L, Nguyen-Tân, Phuc Felix, Rosenthal, David I, Weber, Randal S, Lambert, Louise, Trotti, Andy M, Barrett, William L, Thorstad, Wade L, Yom, Sue S, Wong, Stuart J, Ridge, John A, Rao, Shyam S D, Spencer, Sharon, Fortin, Andre, Raben, David, Harris, Jonathan, Le, Quynh-Thu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594017/
https://ncbi.nlm.nih.gov/pubmed/30913305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32025
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