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Haploinsufficiency of UNC13D increases the risk of lymphoma

BACKGROUND: Experimental models have demonstrated that immune surveillance by cytotoxic lymphocytes can protect from spontaneous neoplasms and cancer. In humans, defective lymphocyte cytotoxicity is associated with the development of hemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer
Main Authors: Löfstedt, Alexandra, Ahlm, Clas, Tesi, Bianca, Bergdahl, Ingvar A., Nordenskjöld, Magnus, Bryceson, Yenan T., Henter, Jan‐Inge, Meeths, Marie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593970/
https://ncbi.nlm.nih.gov/pubmed/30758854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32011
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