Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta

Intrahepatic cholestasis of pregnancy (ICP) causes increased transfer of maternal bile acids to the fetus and an increased incidence of sudden fetal death. Treatment includes ursodeoxycholic acid (UDCA), but it is not clear if UDCA protects the fetus. This study explores the placental transport of t...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Lofthouse, Emma M., Torrens, Christopher, Manousopoulou, Antigoni, Nahar, Monica, Cleal, Jane K., O’Kelly, Ita M., Sengers, Bram G., Garbis, Spiros D., Lewis, Rohan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593889/
https://ncbi.nlm.nih.gov/pubmed/30922127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900015RR
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