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Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model

Aromatase inhibitors are the preferred treatment for certain women with estrogen receptor (ER)-positive breast cancer, but evidence suggests that women with obesity experience aromatase inhibitor resistance at higher rates. To compare how stromal cells derived from women who are lean or obese influe...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Morgan, Molly M., Arendt, Lisa M., Alarid, Elaine T., Beebe, David J., Johnson, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593876/
https://ncbi.nlm.nih.gov/pubmed/31002529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802347RRR
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