Tuning T‐Cell Receptor Affinity to Optimize Clinical Risk‐Benefit When Targeting Alpha‐Fetoprotein–Positive Liver Cancer

Patients with hepatocellular carcinoma (HCC) have a poor prognosis and limited therapeutic options. Alpha‐fetoprotein (AFP) is often expressed at high levels in HCC and is an established clinical biomarker of the disease. Expression of AFP in nonmalignant liver can occur, particularly in a subset of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatology
Prif Awduron: Docta, Roslin Y., Ferronha, Tiago, Sanderson, Joseph P., Weissensteiner, Thomas, Pope, George R., Bennett, Alan D., Pumphrey, Nicholas J., Ferjentsik, Zoltan, Quinn, Laura L., Wiedermann, Guy E., Anderson, Victoria E., Saini, Manoj, Maroto, Miguel, Norry, Elliot, Gerry, Andrew B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593660/
https://ncbi.nlm.nih.gov/pubmed/30561769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30477
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