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Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design

BACKGROUND: Osteoarthritis (OA) leads to joint failure and total joint replacement (TJR, either hip (H) or knee (K)). Worsening of pain and joint space narrowing are believed to be surrogates for joint failure; however, we hypothesize that TJR, as a reflection of joint failure, can be used as an end...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Bager, Cecilie L., Karsdal, Morten, Bihlet, Asger, Thudium, Christian, Byrjalsen, Inger, Bay-Jensen, Anne C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593498/
https://ncbi.nlm.nih.gov/pubmed/31238943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2680-3
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