Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix

We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. Using Staphylococcus aureus as a model pathogen, we identified proteins with known DNA-binding activity and uncovered a series of lipopr...

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Pubblicato in:mBio
Autori principali: Kavanaugh, Jeffrey S., Flack, Caralyn E., Lister, Jessica, Ricker, Erica B., Ibberson, Carolyn B., Jenul, Christian, Moormeier, Derek E., Delmain, Elizabeth A., Bayles, Kenneth W., Horswill, Alexander R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593408/
https://ncbi.nlm.nih.gov/pubmed/31239382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01137-19
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