The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly

An amyloid matrix composed of several family 2 cystatins, including the reproductive cystatin CRES, is an integral structure in the mouse epididymal lumen and has proposed functions in sperm maturation and protection. Understanding how CRES amyloid assembles in vitro may provide clues on how the epi...

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Publicat a:Sci Rep
Autors principals: Do, Hoa Quynh, Hewetson, Aveline, Myers, Caitlyn, Khan, Nazmul H., Hastert, Mary Catherine, M. Harsini, Faraz, Latham, Michael P., Wylie, Benjamin J., Sutton, R. Bryan, Cornwall, Gail A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593142/
https://ncbi.nlm.nih.gov/pubmed/31239483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45545-w
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