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Understanding the Dynamics of T-Cell Activation in Health and Disease Through the Lens of Computational Modeling

T cells in the immune system are activated by binding to foreign peptides (from an external pathogen) or mutant peptide (derived from endogenous proteins) displayed on the surface of a diseased cell. This triggers a series of intracellular signaling pathways, which ultimately dictate the response of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCO Clin Cancer Inform
Prif Awduron: Rohrs, Jennifer A., Wang, Pin, Finley, Stacey D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Clinical Oncology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593125/
https://ncbi.nlm.nih.gov/pubmed/30689404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.18.00057
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