Phage antibody library screening for the selection of novel high-affinity human single-chain variable fragment against gastrin receptor: an in silico and in vitro study

BACKGROUND: As a membrane G protein coupled receptors (GPCRs) family, gastrin/cholecystokinin-2 receptor (CCK2R) plays a key role in the initiation and development of gastric cancer. OBJECTIVES: Targeting CCK2R by immunotherapeutics such as single-chain variable fragments (scFvs) may provide an effe...

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Publicado no:Daru
Main Authors: Jalilzadeh-Razin, Sepideh, Mantegi, Malihe, Tohidkia, Mohammad R., Pazhang, Yaghub, Pourseif, Mohammad M., Barar, Jaleh, Omidi, Yadollah
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593017/
https://ncbi.nlm.nih.gov/pubmed/30607886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-018-0233-1
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