Hypoxia-Inducible Factor-1 Is a Determinant of Lobular Structure and Oxygen Consumption in the Liver

OBJECTIVE: Hypoxia-inducible factor is a hypoxia-responsive transcriptional factor that controls the expression of proteins contributing to homeostatic responses to hypoxia. Spatial heterogeneity of tissue oxygenation has been postulated as a determinant of structure and function of hepatic lobules,...

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Pubblicato in:Microcirculation
Autori principali: Tsukada, Kosuke, Tajima, Toshihide, Hori, Shutaro, Matsuura, Tomomi, Johnson, Randall S., Goda, Nobuhito, Suematsu, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592815/
https://ncbi.nlm.nih.gov/pubmed/23252463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12033
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