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Thermal constraints on in vivo optogenetic manipulations
A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive. Commonly-used illumination protocols increased temperature by 0.2–2°C and suppressed spiking in multiple br...
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| Izdano u: | Nat Neurosci |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6592769/ https://ncbi.nlm.nih.gov/pubmed/31209378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0422-3 |
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