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Release parameters during progressive degeneration of dopamine neurons in mouse model reveal earlier impairment of spontaneous than forced behaviors

To determine the role of reduced dopaminergic transmission for declines of forced versus spontaneous behavior, we used a model of Parkinson’s disease with progressive degeneration of dopamine (DA) neurons, the MitoPark mouse. Mice were subjected to rotarod tests of motor coordination, and open field...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Chen, Yuan-Hao, Hsieh, Tsung-Hsun, Kuo, Tung-Tai, Kao, Jen-Hsin, Ma, Kuo-Hsing, Huang, Eagle Yi-Kung, Chou, Yu-Ching, Olson, Lars, Hoffer, Barry J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592720/
https://ncbi.nlm.nih.gov/pubmed/30933310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14702
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