Detecting T cell receptors involved in immune responses from single repertoire snapshots

Hypervariable T cell receptors (TCRs) play a key role in adaptive immunity, recognizing a vast diversity of pathogen-derived antigens. Our ability to extract clinically relevant information from large high-throughput sequencing of TCR repertoires (RepSeq) data is limited, because little is known abo...

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Bibliografische gegevens
Gepubliceerd in:PLoS Biol
Hoofdauteurs: Pogorelyy, Mikhail V., Minervina, Anastasia A., Shugay, Mikhail, Chudakov, Dmitriy M., Lebedev, Yuri B., Mora, Thierry, Walczak, Aleksandra M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592544/
https://ncbi.nlm.nih.gov/pubmed/31194732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000314
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