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Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae

The evolutionarily conserved Target of Rapamycin (TOR) complex-2 (TORC2) is an essential regulator of plasma membrane homeostasis in budding yeast (Saccharomyces cerevisiae). In this yeast, TORC2 phosphorylates and activates the effector protein kinase Ypk1 and its paralog Ypk2. These protein kinase...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Locke, Melissa N., Thorner, Jeremy
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592226/
https://ncbi.nlm.nih.gov/pubmed/31068077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1616999
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