Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

BACKGROUND: Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of elastin may be important to our understanding of disease ph...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: O’Brien, Michael E., Chandra, Divay, Wilson, Robert C., Karoleski, Chad M., Fuhrman, Carl R., Leader, Joseph K., Pu, Jiantao, Zhang, Yingze, Morris, Alison, Nouraie, Seyed, Bon, Jessica, Urban, Zsolt, Sciurba, Frank C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591816/
https://ncbi.nlm.nih.gov/pubmed/31234847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1098-7
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