Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

BACKGROUND: Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of elastin may be important to our understanding of disease ph...

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Sparad:
Bibliografiska uppgifter
I publikationen:Respir Res
Huvudupphovsmän: O’Brien, Michael E., Chandra, Divay, Wilson, Robert C., Karoleski, Chad M., Fuhrman, Carl R., Leader, Joseph K., Pu, Jiantao, Zhang, Yingze, Morris, Alison, Nouraie, Seyed, Bon, Jessica, Urban, Zsolt, Sciurba, Frank C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591816/
https://ncbi.nlm.nih.gov/pubmed/31234847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1098-7
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