Population Pharmacokinetics of Anidulafungin in Critically Ill Patients

A two-compartment pharmacokinetic (PK) population model of anidulafungin was fitted to PK data from 23 critically ill patients (age, 65 years [range, 28 to 81 years]; total body weight [TBW], 75 kg [range, 54 to 168 kg]). TBW was associated with clearance and incorporated into a final population PK...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Luque, S., Hope, W., Campillo, N., Muñoz-Bermúdez, R., Sorli, L., Barceló-Vidal, J., González-Colominas, E., Alvarez-Lerma, F., Masclans, J. R., Montero, M., Horcajada, J. P., Grau, S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591598/
https://ncbi.nlm.nih.gov/pubmed/31061150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00378-19
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