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Multiple Sclerosis patients carry an increased burden of exceedingly rare genetic variants in the inflammasome regulatory genes

The role of rare genetic variation and the innate immune system in the etiology of multiple sclerosis (MS) is being increasingly recognized. Recently, we described several rare variants in the NLRP1 gene, presumably conveying an increased risk for familial MS. In the present study we aimed to assess...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vidmar, Lovro, Maver, Ales, Drulović, Jelena, Sepčić, Juraj, Novaković, Ivana, Ristič, Smiljana, Šega, Saša, Peterlin, Borut
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591387/
https://ncbi.nlm.nih.gov/pubmed/31235738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45598-x
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