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Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2

The generation of definitive endoderm (DE) cells in sufficient numbers is a prerequisite for cell-replacement therapy for liver and pancreatic diseases. Previously, we reported that human adipose-derived mesenchymal stem cells (hAMSCs) can be induced to DE lineages and subsequent functional cells. C...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Li, Jing, Yang, Yanlei, Fan, Junfen, Xu, Haoying, Fan, Linyuan, Li, Hongling, Zhao, Robert Chunhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591386/
https://ncbi.nlm.nih.gov/pubmed/31235689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1738-3
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