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Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer
G protein-coupled receptors (GPCRs) can integrate extracellular signals via allosteric interactions within dimers and higher-order oligomers. However, the structural bases of these interactions remain unclear. Here, we use the GABA(B) receptor heterodimer as a model as it forms large complexes in th...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591306/ https://ncbi.nlm.nih.gov/pubmed/31235691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10834-5 |
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