A novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival

Autophagy is a conserved lysosomal-dependent cellular degradation process and its dysregulation has been linked to numerous diseases including neurodegeneration, infectious diseases, and cancer. Modulation of autophagy is therefore considered as an attractive target for disease intervention. We carr...

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Publicado no:Sci Rep
Main Authors: Paha, Jiraporn, Kanjanasirirat, Phongthon, Munyoo, Bamroong, Tuchinda, Patoomratana, Suvannang, Naravut, Nantasenamat, Chanin, Boonyarattanakalin, Kanokthip, Kittakoop, Prasat, Srikor, Sirawit, Kongklad, Gunganist, Rangkasenee, Noppawan, Hongeng, Suradej, Utaisincharoen, Pongsak, Borwornpinyo, Suparerk, Ponpuak, Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591302/
https://ncbi.nlm.nih.gov/pubmed/31235856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45641-x
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