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In vivo measurements reveal a single 5′-intron is sufficient to increase protein expression level in Caenorhabditis elegans
Introns can increase gene expression levels using a variety of mechanisms collectively referred to as Intron Mediated Enhancement (IME). IME has been measured in cell culture and plant models by quantifying expression of intronless and intron-bearing reporter genes in vitro. We developed hardware an...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591249/ https://ncbi.nlm.nih.gov/pubmed/31235724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45517-0 |
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