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Propensity of a picornavirus polymerase to slip on potyvirus-derived transcriptional slippage sites

The substitution rates of viral polymerases have been studied extensively. However less is known about the tendency of these enzymes to ‘slip’ during RNA synthesis to produce progeny RNAs with nucleotide insertions or deletions. We recently described the functional utilization of programmed polymera...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Stewart, Hazel, Olspert, Allan, Butt, Benjamin G., Firth, Andrew E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591135/
https://ncbi.nlm.nih.gov/pubmed/30507373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001189
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