Clinical Genomic Profiling Identifies TYK2 Mutation and Overexpression in Patients With Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise at an estimated frequency of 8% to 13% in individuals with neurofibromatosis type 1 (NF1). Compared with their sporadic counterparts, NF1-associated MPNSTs (NF1-MPNSTs) develop in young adults, frequentl...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer
Main Authors: Hirbe, Angela C., Kaushal, Madhurima, Sharma, Mukesh Kumar, Dahiya, Sonika, Pekmezci, Melike, Perry, Arie, Gutmann, David H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591019/
https://ncbi.nlm.nih.gov/pubmed/27875628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30455
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki