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Lidocaine attenuation testing: An in vivo investigation of putative LQT3-associated variants in the SCN5A-encoded sodium channel
BACKGROUND: Long QT syndrome type 3 (LQT3) accounts for 5%–10% of long QT syndrome and results from gain-of-function mutations in the SCN5A-encoded sodium channel. Approximately 2% of healthy individuals host rare SCN5A variants of uncertain significance (VUS). Distinction of true LQT3-causative mut...
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| Pubblicato in: | Heart Rhythm |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590893/ https://ncbi.nlm.nih.gov/pubmed/28412158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2017.04.020 |
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