Ultrasmall superparamagnetic nanoparticles targeting E-selectin: synthesis and effects in mice in vitro and in vivo

Purpose: We developed a contrast agent for targeting E-selectin expression. We detected the agent using magnetic resonance imaging (MRI) in vivo in nude mice that had undergone nasopharyngeal carcinoma (NPC) metastasis. Methods: Sialyl Lewis X (sLe(X)) was conjugated with ultrasmall superparamagneti...

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Опубликовано в: :Int J Nanomedicine
Главные авторы: Liu, Lijuan, Liu, Lu, Li, Yin, Huang, Xiaoxin, Gu, Donglian, Wei, Bo, Su, Danke, Jin, Guanqiao
Формат: Artigo
Язык:Inglês
Опубликовано: Dove 2019
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590629/
https://ncbi.nlm.nih.gov/pubmed/31354271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S199571
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